Description

(-)-B-Chlorodiisopinocampheylborane is a highly valuable chiral organoborane reagent, specifically the enantiomer derived from (+)-α-pinene. This compound matters for its exceptional stereoselectivity, serving as a cornerstone for the asymmetric synthesis of chiral alcohols and other critical intermediates. Pharmaceutical, agrochemical, and advanced materials researchers need it to introduce precise stereochemistry into complex molecules, enabling the production of enantiomerically pure active ingredients and fine chemicals.

Application

• Asymmetric Synthesis of Chiral Alcohols: As a key reagent for the enantioselective reduction of prochiral ketones.
• Pharmaceutical Intermediate Production: For the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Development: In the creation of stereochemically defined pesticides and herbicides.
• Fine Chemical and Fragrance Manufacturing: To produce high-value chiral flavor and fragrance compounds.
• Academic and R&D Laboratories: As a standard reagent for methodological development in organic and medicinal chemistry.
• Material Science Research: For the synthesis of chiral ligands, catalysts, and advanced polymeric materials.

Basic Information

Product Name	(-)-B-Chlorodiisopinocampheylborane
CAS No.	85166-37-6
Molecular Formula	C20H34BCl
Molecular Weight	320.75 g/mol
Synonyms	(-)-B-Chlorodiisopinocampheylborane; (1R)-(-)-B-Chlorodiisopinocampheylborane; (-)-Chlorodiisopinocampheylborane; DIP-Chloride™; (Ipc)2BCl; (-)-Dichloropinanylborane (common misnomer); (1R,2S,5R)-(-)-2,6,6-Trimethylbicyclo[3.1.1]hept-2-ylborane derivative
EINECS	Contact for details

Quality Control

Our (-)-B-Chlorodiisopinocampheylborane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by NMR and HPLC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding asymmetric synthesis. Certificates of Analysis (COA) with full characterization data are provided to guarantee reproducible performance and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated place. Due to its hygroscopic and easily oxidized nature, the container must be carefully sealed after each use to exclude moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (IR)	Conforms to structure
Assay (NMR)	≥ 95.0%
Enantiomeric Excess (e.e.)	≥ 99.0%
Solvent (if supplied as solution)	Specified (e.g., Hexanes, Toluene)
Concentration (if supplied as solution)	Specified (e.g., 1.0 M)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.