Description

Bis[(8Alpha,9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate is a high-purity, organocatalytic salt derived from cinchona alkaloids, valued for its role as a chiral phase-transfer catalyst. This compound is essential for enabling highly enantioselective synthetic transformations in fine chemical and pharmaceutical manufacturing. It is primarily required by R&D laboratories and production facilities specializing in the synthesis of active pharmaceutical ingredients (APIs), agrochemicals, and other high-value chiral intermediates.

Application

• Asymmetric Synthesis Catalyst: A key chiral phase-transfer catalyst (PTC) for enantioselective alkylation, Michael addition, and other carbon-carbon bond-forming reactions.
• Pharmaceutical Intermediate Manufacturing: Critical in the production of enantiomerically pure APIs for cardiovascular, neurological, and oncological therapeutics.
• Agrochemical Synthesis: Used in the development of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process chemistry research.
• Fine Chemical Production: Enables the synthesis of complex chiral molecules for flavors, fragrances, and advanced materials.

Basic Information

Product Name	Bis[(8Alpha,9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate
CAS No.	85135-87-1
Molecular Formula	C₄₂H₅₂N₄O₈S
Molecular Weight	772.95 g/mol
Synonyms	Bis(9-Hydroxy-6'-methoxycinchonanium) Sulfate; (8α,9R)-9-Hydroxy-6'-methoxycinchonan-1-ium Sulfate (2:1); Cinchonanium Sulfate Derivative; PTC Catalyst from Cinchona Alkaloid; Chiral Phase-Transfer Catalyst; O-Methylquinidine Sulfate Salt; Bis(O-Methylquinidinium) Sulfate
EINECS	Contact for details

Quality Control

Our Bis[(8Alpha,9R)-9-Hydroxy-6'-Methoxycinchonanium] Sulphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for catalytic applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.