Description

N-(4-Acetyl-2-Fluorophenyl)Acetamide is a specialized fluorinated aromatic intermediate of significant importance in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both an acetyl and a fluorine substituent, making it a versatile building block for creating complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence profiles.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorinated aromatic units.
• Chemical Biology Probes: Utilized in the creation of fluorescent tags or molecular probes for studying biological processes and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	N-(4-Acetyl-2-Fluorophenyl)Acetamide
CAS No.	85117-88-0
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	1-(4-Acetamido-3-fluorophenyl)ethanone; 2'-Fluoro-4'-acetoacetanilide; N-(2-Fluoro-4-acetylphenyl)acetamide; 4-Acetyl-2-fluoroacetanilide; Acetamide, N-(4-acetyl-2-fluorophenyl)-; 85117-88-0; 2-Fluoro-4-acetylacetanilide
EINECS	Contact for details

Quality Control

Our N-(4-Acetyl-2-Fluorophenyl)Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.