Description

(-)-Diisopinocampheyl Chloroborane is a highly versatile and stereoselective chiral borane reagent, essential for asymmetric synthesis. Its primary value lies in its ability to facilitate enantioselective reductions and hydroborations, delivering high optical purity in the resulting products. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the production of chiral intermediates and active ingredients.

Application

• Asymmetric Reduction of Prochiral Ketones: Enantioselective synthesis of secondary alcohols with high enantiomeric excess (ee).
• Chiral Hydroboration of Alkenes: Key step in the synthesis of enantiomerically enriched alkylboranes and subsequent functional groups.
• Pharmaceutical Intermediate Synthesis: Production of chiral building blocks for active pharmaceutical ingredients (APIs).
• Agrochemical Product Development: Creation of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Fragrance Manufacturing: Synthesis of high-value chiral compounds for specialty applications.
• Methodology Development in Academic Research: A staple reagent for developing new catalytic and stoichiometric asymmetric transformations.

Basic Information

Product Name	(-)-Diisopinocampheyl Chloroborane
CAS No.	85116-37-6
Molecular Formula	C20H34BCl
Molecular Weight	320.75 g/mol
Synonyms	(-)-DIP-Chloride™; (1R)-(-)-Diisopinocampheylchloroborane; (1R)-(-)-B-Chlorodiisopinocampheylborane; (1R)-Diisopinocampheylchloroborane; DIP-Chloride; B-Chlorobis((1R,2S,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl)borane; Chlorodiisopinocampheylborane
EINECS	Contact for details

Quality Control

Our (-)-Diisopinocampheyl Chloroborane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by NMR and optical rotation, to ensure consistent performance and high enantioselectivity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, and well-ventilated area. This material is hygroscopic (moisture-sensitive) and easily oxidized; containers must be purged with inert gas before resealing after each use to maintain purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or solution
Identification (IR)	Conforms to structure
Assay (NMR)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC/NMR)	≥ 99.0% ee
Specific Optical Rotation [α]	Contact for details
Solvent (if supplied as solution)	Specified (e.g., Hexane, Toluene)
Concentration (if supplied as solution)	Specified (e.g., 1.0 M)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.