Description

2-(4-Nitrophenyl)-1,3,2-Dioxaborinane is a specialized organoboron reagent featuring a nitro-substituted aromatic ring, widely utilized as a key synthetic building block in modern organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitrophenyl moiety imparts specific biological activity.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex organic molecules via palladium-catalyzed cross-coupling reactions.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Integral to the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-(4-Nitrophenyl)-1,3,2-Dioxaborinane
CAS No.	85107-43-3
Molecular Formula	C9H10BNO4
Molecular Weight	206.99 g/mol
Synonyms	4-Nitrophenyl-1,3,2-dioxaborinane; 2-(4-Nitrophenyl)-1,3,2-dioxaborinane; 1,3,2-Dioxaborinane, 2-(4-nitrophenyl)-; 4-Nitrophenylboronic acid 1,3-propanediol ester; (4-Nitrophenyl)boronic acid 1,3-propanediol cyclic ester; 2-(p-Nitrophenyl)-1,3,2-dioxaborinane; p-Nitrophenyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 2-(4-Nitrophenyl)-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.