Description

2',6'-Difluoropropiophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on new active ingredients, where the introduction of fluorine atoms is critical for modulating biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Advanced Chemical Research: Employed in academic and industrial R&D for exploring new fluorination methodologies and creating specialized chemical libraries.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, high-value fluorinated aromatic structures.

Basic Information

Product Name	2',6'-Difluoropropiophenone
CAS No.	85068-31-1
Molecular Formula	C9H8F2O
Molecular Weight	170.16 g/mol
Synonyms	1-(2,6-Difluorophenyl)propan-1-one; 2,6-Difluoropropiophenone; Propiophenone, 2',6'-difluoro-; α,α,2,6-Tetrafluoropropiophenone (incorrect but sometimes used); 2,6-DFPP
EINECS	Contact for details

Quality Control

Our 2',6'-Difluoropropiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.