Description

(8Alpha,9R)-10,11-Dihydro-6'-Methoxy-5'-Nitrocinchonan-9-Ol is a specialized, high-purity chiral compound belonging to the cinchona alkaloid derivative family. This chemical is of significant value as a key intermediate or chiral building block in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring high stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or cardiovascular conditions.
• Asymmetric Catalyst Ligand: Used to develop or as part of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Synthesis: Serves as a sophisticated building block for creating complex organic molecules in research and development laboratories.
• Agrochemical Research: Employed in the development of novel, optically active pesticides and herbicides.
• Analytical Chemistry Standard: Can be utilized as a reference standard for method development and quality control in chiral separation techniques like HPLC.
• Academic & Industrial R&D: Fundamental material for studying stereochemistry and developing new synthetic methodologies.

Basic Information

Product Name	(8Alpha,9R)-10,11-Dihydro-6'-Methoxy-5'-Nitrocinchonan-9-Ol
CAS No.	84946-09-8
Molecular Formula	C20H23N3O4
Molecular Weight	369.42 g/mol
Synonyms	10,11-Dihydro-6'-methoxy-5'-nitrocinchonan-9-ol (8α,9R)-; (8α,9R)-10,11-Dihydro-6'-methoxy-5'-nitrocinchonan-9-ol; 5'-Nitro-10,11-dihydro-6'-methoxycinchonan-9-ol; Dihydro-6'-methoxy-5'-nitrocinchonan-9-ol; A derivative of Cinchonan-9-ol; Nitrocinchonan derivative; Chiral cinchona alkaloid intermediate.
EINECS	Contact for details

Quality Control

Our (8Alpha,9R)-10,11-Dihydro-6'-Methoxy-5'-Nitrocinchonan-9-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.