Description

1-Trimethylsilyl-4-T-Butyl-1,3-Butadiyne is a specialized organosilicon compound featuring a unique diyne structure protected by bulky silyl and tert-butyl groups. This compound matters as a versatile and valuable building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel polymers, ligands, and active pharmaceutical ingredients.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those requiring rigid, linear alkyne spacers.
• Agrochemical Synthesis: Serves as a key precursor for creating advanced crop protection agents with specific structural motifs.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent for developing specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Organic Synthesis Building Block: Utilized in Sonogashira coupling, click chemistry, and other cross-coupling reactions to introduce protected diyne functionalities.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for transition metal catalysis.
• Academic & Industrial R&D: A critical reagent for exploratory chemistry in university and corporate research laboratories.

Basic Information

Item	Details
Product Name	1-Trimethylsilyl-4-T-Butyl-1,3-Butadiyne
CAS No.	84751-19-9
Molecular Formula	C11H20Si
Molecular Weight	180.36 g/mol
Synonyms	1-(Trimethylsilyl)-4-(tert-butyl)-1,3-butadiyne; 4-tert-Butyl-1-trimethylsilyl-1,3-butadiyne; tert-Butyl(trimethylsilyl)butadiyne; TMS-TBD; 1,3-Butadiyne, 1-(trimethylsilyl)-4-(1,1-dimethylethyl)-; (Tert-Butyl)(Trimethylsilyl)Diyne
EINECS	Contact for details

Quality Control

Our production of 1-Trimethylsilyl-4-T-Butyl-1,3-Butadiyne adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and scale-up applications. Quality is verified through comprehensive analytical techniques including GC, HPLC, NMR, and FTIR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.