Description

2-Chloro-4-Methoxy-3-Oxo-Butanoic Acid Methyl Ester is a versatile and high-purity chemical intermediate with significant synthetic utility. Its unique molecular structure, featuring both chloro and methoxy substituents on a β-keto ester framework, makes it a valuable building block for constructing complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex heterocyclic or chiral centers.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its reactive chloro and keto groups.
• Fine Chemical Manufacturing: Serves as a specialized building block for creating dyes, pigments, and performance chemicals requiring specific functional group transformations.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new carbon-carbon bond formation and cyclization reactions.
• Chiral Auxiliary/Resolving Agent Precursor: Its structure can be modified to create chiral auxiliaries used in asymmetric synthesis to produce enantiomerically pure compounds.

Basic Information

Product Name	2-Chloro-4-Methoxy-3-Oxo-Butanoic Acid Methyl Ester
CAS No.	84746-34-9
Molecular Formula	C7H11ClO4
Molecular Weight	194.61 g/mol
Synonyms	Methyl 2-chloro-4-methoxy-3-oxobutanoate; 2-Chloro-4-methoxy-3-oxobutyric acid methyl ester; Methyl 2-chloroacetoacetate 4-methyl ether; Butanoic acid, 2-chloro-4-methoxy-3-oxo-, methyl ester; Acetoacetic acid, 2-chloro-4-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxy-3-Oxo-Butanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.