Description

2-[[p-(Phenylazo)Benzyl]Sulphonyl]Ethyl S-(Acetamidomethyl)-L-Cysteinate, Mono(Trifluoroacetate) is a specialized, high-purity chemical intermediate designed for advanced research and pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of novel therapeutic agents and biochemical probes. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, targeted drug delivery systems, and proteomics research.

Application

• Peptide Synthesis Intermediate: Acts as a critical reagent in solid-phase and solution-phase peptide synthesis, particularly for introducing specialized functional groups.
• Bioconjugation Chemistry: Used for site-specific labeling and modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Protease Inhibitor Development: Serves as a precursor or model compound in the research and development of enzyme inhibitors targeting cysteine proteases.
• Linker Molecule for Drug Delivery: Employed in the design of prodrugs and antibody-drug conjugates (ADCs) due to its cleavable disulfide-like linkage potential.
• Biochemical Research: Utilized as a tool compound in studies of redox biology and thiol-mediated cellular processes.
• Material Science: Investigated for creating functionalized surfaces and polymers with specific biorecognition properties.

Basic Information

Product Name	2-[[p-(Phenylazo)Benzyl]Sulphonyl]Ethyl S-(Acetamidomethyl)-L-Cysteinate, Mono(Trifluoroacetate)
CAS No.	84712-95-8
Molecular Formula	C₂₂H₂₅F₃N₄O₆S₂
Molecular Weight	562.58 g/mol
Synonyms	S-(Acetamidomethyl)-L-cysteine 2-[[4-(Phenylazo)benzyl]sulfonyl]ethyl ester trifluoroacetate; L-Cysteine, S-[(acetylamino)methyl]-, 2-[[[4-(phenylazo)phenyl]methyl]sulfonyl]ethyl ester, 2,2,2-trifluoroacetate (1:1); Acetamidomethyl-L-cysteinyl-[p-(phenylazo)benzyl]sulfonylethyl ester TFA salt; AAMC-[p-azobenzyl]sulfonylethyl ester TFA; Peptide synthesis reagent 84712-95-8
EINECS	Contact for details

Quality Control

Our production of 2-[[p-(Phenylazo)Benzyl]Sulphonyl]Ethyl S-(Acetamidomethyl)-L-Cysteinate, Mono(Trifluoroacetate) adheres to stringent quality protocols suitable for research and pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.