Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R,5S)- (9Ci) is a high-value, chiral building block characterized by its protected aldehyde functionality and defined stereochemistry. This compound is essential for the synthesis of complex molecules where precise stereocontrol is critical. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, leveraging its stereochemistry for enhanced biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, particularly in reactions involving protected carbonyl groups.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R,5S)- (9Ci)
CAS No.	84519-53-9
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (4R-cis)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carbaldehyde; D-Glyceraldehyde Acetonide; (R)-Glyceraldehyde Acetonide; (4R,5S)-2,2,5-Trimethyl-[1,3]dioxolane-4-carbaldehyde; (4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde (9CI)
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R,5S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are characterized by advanced analytical techniques including chiral HPLC, NMR, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.