Description

1-Acetyl-2-Bromopyrrole is a versatile brominated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functional complexity at the pyrrole nucleus.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging its halogenated pyrrole structure.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Chemical Research: An invaluable building block for cross-coupling reactions (e.g., Suzuki, Stille) and further functionalization to create diverse pyrrole libraries for screening.
• Dye and Pigment Industry: Employed in the synthesis of specialized heterocyclic dyes and pigments with unique optical properties.

Basic Information

Product Name	1-Acetyl-2-Bromopyrrole
CAS No.	84455-06-1
Molecular Formula	C6H6BrNO
Molecular Weight	188.02 g/mol
Synonyms	2-Bromo-1-acetylpyrrole; 2-Bromo-1H-pyrrol-1-yl ethanone; 1-(2-Bromo-1H-pyrrol-1-yl)ethanone; 2-Bromopyrrole-1-acetic acid methyl ester (common misnomer); N-Acetyl-2-bromopyrrole; Ethanone, 1-(2-bromo-1H-pyrrol-1-yl)-; 2-Bromo-N-acetylpyrrole
EINECS	Contact for details

Quality Control

Our 1-Acetyl-2-Bromopyrrole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research-grade precision.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.