Description

2,2-Difluoro-Acetic Acid, Hydrazide is a specialized fluorinated hydrazide derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluoroacetate moiety linked to a hydrazide functional group, makes it a valuable precursor for the development of novel heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in pharmaceutical chemistry, agrochemical development, and materials science, where precise fluorination is required to modulate biological activity and material properties.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of fluorinated pyrazoles, pyridazines, and other nitrogen-containing heterocycles with potential therapeutic applications.
• Agrochemical Research: Used in creating novel fluorinated active ingredients for herbicides, fungicides, and insecticides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Material Science Precursor: Employed in the development of specialty polymers and liquid crystals where the difluoromethyl group can influence thermal stability and dielectric properties.
• Chemical Biology & Proteomics: Acts as a reactive handle in bioconjugation chemistry and as a scaffold for designing enzyme inhibitors or molecular probes.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new C-F bond formation reactions and the synthesis of complex fluorinated molecules.

Basic Information

Product Name	2,2-Difluoro-Acetic Acid, Hydrazide
CAS No.	84452-98-2
Molecular Formula	C2H4F2N2O
Molecular Weight	110.06 g/mol
Synonyms	2,2-Difluoroacetohydrazide; Difluoroacetic Acid Hydrazide; 2,2-Difluoroacetyl Hydrazine; Hydrazine, (2,2-difluoroacetyl)-; Acetic acid, 2,2-difluoro-, hydrazide; (Difluoroacetyl)hydrazine; NSC 403796
EINECS	Contact for details

Quality Control

Every batch of 2,2-Difluoro-Acetic Acid, Hydrazide is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and opened under a dry atmosphere to minimize degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.