Description

2-Carbomethoxy-A-Nor-5 α-Cholestan-3-One is a high-purity, synthetic steroid derivative with a modified cholestane backbone, serving as a critical advanced intermediate in pharmaceutical research and development. This compound is valued for its defined stereochemistry and functional groups, which make it a versatile building block for synthesizing novel steroid-based therapeutics and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel steroid hormone analogs and receptor modulators.
• Research Chemical: Used in academic and industrial R&D for studying steroid biosynthesis pathways and structure-activity relationships (SAR).
• Reference Standard: Serves as an analytical standard for quality control and method development in steroid analysis using HPLC or GC-MS.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for biological screening and drug discovery programs.

Basic Information

Product Name	2-Carbomethoxy-A-Nor-5 α-Cholestan-3-One
CAS No.	84393-64-6
Molecular Formula	C₂₉H₄₈O₃
Molecular Weight	444.70 g/mol
Synonyms	2-Carbomethoxy-A-nor-5α-cholestan-3-one; Methyl 3-oxo-A-nor-5α-cholestane-2-carboxylate; A-Nor-5α-cholestane-2-carboxylic acid, 3-oxo-, methyl ester; 3-Oxo-A-nor-5α-cholestane-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Carbomethoxy-A-Nor-5 α-Cholestan-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.