Description

6 Alpha,16 α-Dihydroxyestrone 6-Hemisuccinate is a high-purity, synthetically derived steroid derivative, specifically a hemisuccinate ester of a dihydroxyestrone isomer. This compound is of significant value as a key pharmaceutical intermediate and a critical reference standard for analytical research and development. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for the production and quality control of advanced steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, LC-MS, and other chromatographic systems.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations related to steroid hormones.
• Process Development & Scale-up: Employed in R&D for optimizing synthetic routes and scaling production processes for novel steroid derivatives.
• Metabolite Standard: Used as a standard for identifying and quantifying specific estrogen metabolites in clinical and preclinical studies.

Basic Information

Product Name	6 Alpha,16 α-Dihydroxyestrone 6-Hemisuccinate
CAS No.	84371-31-3
Molecular Formula	C23H30O7
Molecular Weight	418.48 g/mol
Synonyms	6α,16α-Dihydroxyestrone 6-hemisuccinate; Estrone, 6,16-dihydroxy-, 6-hemisuccinate, (6α,16α)-; 6α,16α-Dihydroxy-1,3,5(10)-estratrien-17-one 6-hemisuccinate; 6,16α-Dihydroxyestrone 6-hemisuccinate; 6-Hemisuccinyloxy-6α,16α-dihydroxyestrone; 6α,16α-Dihydroxyestrone 6-(hydrogen succinate); (6α,16α)-6,16-Dihydroxyestrone 6-Hemisuccinate
EINECS	Contact for details

Quality Control

Our 6 Alpha,16 α-Dihydroxyestrone 6-Hemisuccinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available for every lot upon request, providing full traceability and compliance assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.