Description

4-Hydroxy-2-Methoxybenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both phenolic and methoxy substituents, makes it a valuable intermediate for creating complex molecules with specific functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with benzophenone or benzofuran cores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its nitrile and phenolic groups for structural modification.
• Dye and Pigment Manufacturing: Serves as an intermediate for creating specialized dyes, pigments, and optical brighteners due to its aromatic ring system.
• Liquid Crystal Materials: Acts as a building block for mesogenic compounds used in display technologies.
• Polymer Chemistry: Can be incorporated as a monomer or cross-linking agent to impart specific thermal or chemical resistance properties to polymers.
• Organic Synthesis Research: A valuable reagent for academic and industrial R&D in constructing complex heterocycles and natural product analogs.

Basic Information

Product Name	4-Hydroxy-2-Methoxybenzonitrile
CAS No.	84224-29-3
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	2-Methoxy-4-hydroxybenzonitrile; 4-Cyano-3-methoxyphenol; Vanillonitrile; 3-Methoxy-4-hydroxybenzonitrile; 4-Hydroxy-3-methoxybenzonitrile; 2-Methoxy-4-cyanophenol; 4-Cyanoguaiacol; 2-Methoxy-4-cyanophenol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Methoxybenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.