Description

3-(Benzyloxy)Cyclobutane-1,1-Dicarboxylic Acid is a high-purity, functionalized cyclobutane derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique structural features, offering a rigid cyclobutane core with both a benzyl-protected alcohol and two carboxylic acid handles, enabling precise molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for constructing constrained analogs and prodrugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the cyclobutane ring can impart favorable biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts in asymmetric synthesis, leveraging its prochiral center and functional group diversity.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, such as polyamides or polyesters, with tailored thermal and mechanical properties.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic chemistry, including ring-opening, decarboxylation, and cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.

Basic Information

Item	Details
Product Name	3-(Benzyloxy)Cyclobutane-1,1-Dicarboxylic Acid
CAS No.	84182-46-7
Molecular Formula	C14H16O5
Molecular Weight	264.27 g/mol
Synonyms	1,1-Cyclobutanedicarboxylic acid, 3-(phenylmethoxy)-; 3-(Benzyloxy)cyclobutane-1,1-dicarboxylic acid; 3-Benzyloxy-1,1-cyclobutanedicarboxylic acid; 3-O-Benzyl-1,1-cyclobutanedicarboxylic acid; Cyclobutane-1,1-dicarboxylic acid, 3-(benzyloxy)-; 84182-46-7
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)Cyclobutane-1,1-Dicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, from early-stage R&D to cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.