Description

1-Formyl-Piperidine-4-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. Pharmaceutical research and development laboratories, as well as fine chemical manufacturers, need this high-purity intermediate to streamline their synthetic routes and accelerate drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of piperidine-based active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening for new therapeutic agents.
• Chemical Synthesis: Serves as a protected form of isonipecotic acid, facilitating selective reactions at other functional groups on the piperidine ring.
• Agrochemical Development: Employed in the research and synthesis of novel pesticides and herbicides that utilize the piperidine motif.
• Ligand and Catalyst Design: Useful for creating complex ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for methodological studies and the development of new synthetic transformations in organic chemistry.

Basic Information

Product Name	1-Formyl-Piperidine-4-Carboxylic Acid
CAS No.	84163-42-8
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	4-Carboxy-1-formylpiperidine; 1-Formylisonipecotic Acid; 1-Formyl-4-piperidinecarboxylic Acid; 4-Piperidinecarboxylic Acid, 1-formyl-; N-Formylisonipecotic Acid; Isonipecotic Acid N-Formyl Derivative; 1-Carbamoylpiperidine-4-carboxylic Acid (tautomer)
EINECS	Contact for details

Quality Control

Our 1-Formyl-Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.