Description

4-(2,4-Difluoro-Benzoyl)-Piperidine-1-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorobenzoyl and piperidine carbaldehyde functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic categories.
• Organic Synthesis Reagent: Used in research-scale and pilot-scale organic reactions, including amide bond formation and nucleophilic addition reactions.
• Agrochemical Research: Serves as a precursor in the development of new agrochemicals with enhanced activity and selectivity.
• Material Science: Investigated for the preparation of specialty polymers and ligands for catalytic systems.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects and process development.

Basic Information

Product Name	4-(2,4-Difluoro-Benzoyl)-Piperidine-1-Carbaldehyde
CAS No.	84162-80-1
Molecular Formula	C13H13F2NO2
Molecular Weight	253.25 g/mol
Synonyms	1-Formyl-4-(2,4-difluorobenzoyl)piperidine; 4-(2,4-Difluorobenzoyl)piperidine-1-carboxaldehyde; Piperidine-1-carbaldehyde, 4-(2,4-difluorobenzoyl)-; 4-(2,4-Difluorobenzoyl)-1-piperidinecarboxaldehyde; 1-Piperidinecarboxaldehyde, 4-(2,4-difluorobenzoyl)-
EINECS	Contact for details

Quality Control

Our 4-(2,4-Difluoro-Benzoyl)-Piperidine-1-Carbaldehyde is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.