Description

4,4,4-Trifluorobutylamine Hydrochloride is a high-purity fluorinated amine salt, a key building block in modern synthetic chemistry. Its value lies in the introduction of the trifluoromethyl group, which can dramatically alter the physicochemical properties of target molecules, enhancing metabolic stability and lipophilicity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated amine moiety to improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to enhanced activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, influencing dielectric anisotropy and stability.
• Fluorinated Surfactant & Polymer Research: Employed in the creation of specialty surfactants and polymers with unique surface properties and chemical resistance.
• Peptide Modification & Bioconjugation: Utilized to incorporate fluorine tags or modify peptides, aiding in metabolic studies and the development of diagnostic probes.
• Organic Synthesis & Catalysis: Acts as a versatile reagent for introducing the 4,4,4-trifluorobutyl group into complex organic frameworks in medicinal and materials chemistry.

Basic Information

Product Name	4,4,4-Trifluorobutylamine Hydrochloride
CAS No.	84153-82-2
Molecular Formula	C4H9F3N · HCl
Molecular Weight	173.57 g/mol
Synonyms	1-Amino-4,4,4-trifluorobutane Hydrochloride; 4,4,4-Trifluorobutan-1-amine Hydrochloride; 4,4,4-Trifluoro-1-butanamine Hydrochloride; 4,4,4-Trifluorobutylammonium Chloride; Butanamine, 4,4,4-trifluoro-, hydrochloride; γ,γ,γ-Trifluorobutylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluorobutylamine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, NMR, and Karl Fischer titration. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.