Description

2-Methylpropaneboronic Acid (1S,2S,3R,5S)-(+)-2,3-Pinanediol Ester is a high-purity, chiral boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a protected boronic acid, offering enhanced stability and stereochemical control for complex cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced chiral intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, especially in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral APIs where stereochemical integrity is paramount.
• Asymmetric Synthesis: Serves as a chiral auxiliary or reagent in catalytic asymmetric transformations.
• Fine Chemical and Agrochemical Production: Employed in the development of high-value specialty chemicals and advanced crop protection agents.
• Material Science Research: A precursor for creating novel organic electronic materials and polymers with specific properties.
• Process Development and Scale-up: Used in R&D for optimizing synthetic routes from laboratory to pilot and commercial scale.

Basic Information

Product Name	2-Methylpropaneboronic Acid (1S,2S,3R,5S)-(+)-2,3-Pinanediol Ester
CAS No.	84110-34-9
Molecular Formula	C₁₄H₂₅BO₂
Molecular Weight	236.16 g/mol
Synonyms	(+)-Pinanediol Isopropylboronate; (1S,2S,3R,5S)-(-)-2,10-Pinanediol Isopropylboronate; Isopropylboronic Acid Pinanediol Ester; (1S,2S,3R,5S)-(+)-Pinanediol 2-Methylpropaneboronate; 2-Methylpropane-1-boronic Acid Pinanediol Ester; Isopropaneboronic Acid Pinacol Ester (related class); (1S)-(+)-Pinanediol Isopropylboronic Ester
EINECS	Contact for details

Quality Control

Our 2-Methylpropaneboronic Acid (1S,2S,3R,5S)-(+)-2,3-Pinanediol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC and NMR spectroscopy, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.