Description

Wilforlide A is a bioactive triterpenoid compound isolated from the traditional medicinal plant *Tripterygium wilfordii* (Thunder God Vine). This high-purity reference standard is critical for pharmaceutical research and development, particularly in the study of anti-inflammatory and immunosuppressive mechanisms. It serves as an essential analytical standard for quality control in the production of botanical extracts and advanced pharmaceutical intermediates. Researchers and manufacturers in the phytopharmaceutical, nutraceutical, and academic sectors rely on it for its consistent biological activity and structural integrity.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of herbal extracts and finished products.
• Bioactivity Research: Employed in preclinical studies to investigate its immunosuppressive, anti-inflammatory, and potential anti-tumor properties.
• Natural Product Isolation & Synthesis: Serves as a key marker compound for the standardization of *Tripterygium wilfordii* extracts and as a lead compound for synthetic analog development.
• Quality Control in Nutraceuticals: Acts as a biomarker for ensuring the potency, authenticity, and batch-to-batch consistency of thunder god vine-based dietary supplements.
• Academic & Institutional Research: Utilized in universities and research institutes for pharmacological, toxicological, and metabolic pathway studies.

Basic Information

Product Name	Wilforlide A
CAS No.	84104-71-2
Molecular Formula	C30H46O3
Molecular Weight	454.69 g/mol
Synonyms	Wilforlide A; (3S,4aR,6aR,6bS,8aS,12aS,12bR,14aS,14bS)-4,4,6a,6b,8a,12a,14b-Octamethyl-11-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-docosahydropicene-3-carboxylic acid; 3β-Hydroxy-25-nor-friedel-3,1(10)-dien-2-one-29-oic acid; Triptobenzene H; Celastrol derivative; Tripterygium wilfordii lactone A
EINECS	Contact for details

Quality Control

Our Wilforlide A is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade standards. Our quality system is designed to meet the rigorous demands of pharmaceutical development and analytical laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool environment. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.