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2,3-Dihydro-2,3-(N(5)-Formyl-2',5',6'-Triamino-4-Oxo-N(5)-Pyrimidyl)-3-Hydroxyaflatoxin B(1) CAS NO 83953-67-7
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CAS No.:83953-67-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,3-Dihydro-2,3-(N(5)-Formyl-2',5',6'-Triamino-4-Oxo-N(5)-Pyrimidyl)-3-Hydroxyaflatoxin B(1) is a chemically modified derivative of aflatoxin B1, a potent mycotoxin, designed for advanced research and analytical applications. This compound is of significant value for scientists studying mycotoxin metabolism, detoxification pathways, and the development of detection methods. It serves as a critical reference standard and research reagent for toxicology laboratories, food safety testing facilities, and academic institutions focused on fungal contamination and chemical safety.
Application
- Analytical Reference Standard: Primary use as a certified reference material (CRM) for the calibration and validation of analytical instruments like HPLC, LC-MS/MS, and ELISA kits in mycotoxin testing.
- Metabolic Pathway Research: Investigation of the biotransformation and metabolic fate of aflatoxin B1 in biological systems, including studies on liver enzymes.
- Toxicological Studies: Used in in vitro and in vivo research to understand the comparative toxicity and mechanism of action of aflatoxin derivatives.
- Method Development: Essential for developing and optimizing new, sensitive chromatographic or immunoassay-based methods for contaminant detection in complex matrices.
- Food & Feed Safety: Supports quality control programs in the agriculture, nut, grain, and dairy industries to ensure regulatory compliance for aflatoxin levels.
- Biomarker Research: Potential use in studies aiming to identify and quantify specific aflatoxin-DNA or protein adducts as exposure biomarkers.
Basic Information
| Product Name | 2,3-Dihydro-2,3-(N(5)-Formyl-2',5',6'-Triamino-4-Oxo-N(5)-Pyrimidyl)-3-Hydroxyaflatoxin B(1) |
| CAS No. | 83953-67-7 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 2,3-Dihydro-2,3-(N(5)-formyl-2',5',6'-triamino-4-oxo-N(5)-pyrimidyl)-3-hydroxyaflatoxin B1; Aflatoxin B1 2,3-dihydro-2,3-(N(5)-formyl-2',5',6'-triamino-4-oxo-N(5)-pyrimidyl)-3-hydroxy derivative; Modified Aflatoxin B1 Derivative; AFB1 Formamidopyrimidine Adduct (Analog); Aflatoxin B1 Formyltriaminopyrimidyl Hydroxy Derivative; 83953-67-7; Research Grade Aflatoxin Derivative |
| EINECS | Contact for details |
Quality Control
Every batch of our high-purity research chemicals undergoes rigorous analytical testing to ensure identity, purity, and consistency. Quality is verified using advanced techniques including HPLC and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment, supporting traceability and compliance with GLP (Good Laboratory Practice) standards for research applications.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 95% (Area Percent) |
| Water Content (KF) | ≤ 2.0% |
| Solubility | Soluble in DMSO, Methanol |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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