Description

4-Azido-3-Nitrophenyl-Azo-(5-Hydroxytryptamine) is a specialized, multi-functional organic compound that serves as a critical building block and probe in advanced chemical research and development. Its unique structure, incorporating azide, nitro, azo, and hydroxytryptamine moieties, makes it a valuable reagent for photoaffinity labeling, bioconjugation, and the synthesis of complex molecular architectures. This compound is essential for researchers and developers in the fields of medicinal chemistry, chemical biology, and materials science. Its precise reactivity profile enables the study of biomolecular interactions and the creation of novel functionalized polymers and dyes.

Application

• Photoaffinity Labeling Probe: Used in biochemical research to covalently capture and identify transient protein-ligand or protein-protein interactions upon photoactivation.
• Bioconjugation Reagent: Serves as a linker for attaching fluorophores, drugs, or other functional groups to biomolecules like antibodies, peptides, or nanoparticles via click chemistry (utilizing the azide group).
• Medicinal Chemistry Intermediate: A key synthetic precursor in the development of novel therapeutic agents, particularly those targeting serotonin-related pathways or requiring azo-based prodrug designs.
• Advanced Materials Synthesis: Employed in the creation of specialty polymers, liquid crystals, or smart materials where the azo group provides photoresponsive properties.
• Analytical Chemistry Standard: Used as a reference standard in chromatographic analysis (HPLC, LC-MS) for method development and quality control in related synthetic processes.
• Dye and Pigment Research: Acts as a precursor for developing novel azo dyes with specific optical properties for high-tech applications.

Basic Information

Product Name	4-Azido-3-Nitrophenyl-Azo-(5-Hydroxytryptamine)
CAS No.	83919-48-6
Molecular Formula	C16H12N8O3
Molecular Weight	364.32 g/mol
Synonyms	5-HT-AAD; 5-Hydroxytryptamine-4-azido-3-nitrophenyl azo adduct; ANP-Azo-5HT; 4-Azido-3-nitroazobenzene-5-hydroxytryptamine; Azidonitrophenyl azo serotonin; Serotonin azidonitrophenyl azo derivative; Photoactivatable serotonin analog; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 4-Azido-3-Nitrophenyl-Azo-(5-Hydroxytryptamine) is synthesized and purified under controlled conditions to ensure high chemical integrity and lot-to-lot consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Comprehensive analysis includes identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). For long-term storage, consider storing desiccated under an inert atmosphere to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Orange to dark red solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.