Description

18α-Glycyrrhetinic Acid (CAS 83896-44-0) is a high-purity pentacyclic triterpenoid derivative and the principal bioactive aglycone of glycyrrhizic acid, sourced from licorice root. This compound is valued for its potent anti-inflammatory, antiviral, and hepatoprotective properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is essential for manufacturers and R&D teams in the pharmaceutical, nutraceutical, and cosmetic industries seeking to develop therapeutic and protective formulations.

Application

• Pharmaceutical Intermediates: Key starting material for synthesizing potent anti-inflammatory drugs, hepatoprotective agents, and antiviral medications.
• Cosmetic & Skincare Actives: Used in formulations for its skin-whitening, anti-aging, and anti-inflammatory effects to soothe irritation and reduce hyperpigmentation.
• Nutraceuticals & Dietary Supplements: Incorporated into supplements for liver support and to enhance immune system function.
• Research & Development: Serves as a reference standard and a crucial compound for pharmacological studies and new drug discovery.
• Veterinary Pharmaceuticals: Applied in animal health products for its therapeutic benefits.

Basic Information

Product Name	18α-Glycyrrhetinic Acid
CAS No.	83896-44-0
Molecular Formula	C30H46O4
Molecular Weight	470.68 g/mol
Synonyms	18α-Glycyrrhetinic Acid; (18α)-Glycyrrhetinic Acid; Enoxolone; 18α-GA; 3β-Hydroxy-11-oxoolean-12-en-30-oic acid; Uralenic Acid; Glycyrrhetic Acid; NSC 36744; BRN 2219145
EINECS	Contact for details

Quality Control

Our 18α-Glycyrrhetinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and cosmetic applications. Certificates of Analysis (COA) documenting full compliance are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.