Description

2-Diazo-3-Ketoglutaric Acid Dimethyl Ester is a specialized diazo compound and a versatile chemical building block in organic synthesis. Its core value lies in its ability to act as a precursor for generating reactive carbene intermediates, facilitating complex carbon-carbon and carbon-heteroatom bond formations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, particularly for the synthesis of heterocyclic compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), especially those containing heterocyclic cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in cyclopropanation, C-H insertion, and other carbene-mediated reactions to construct complex organic frameworks.
• Material Science Research: Serves as a building block for creating novel polymers and functional materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Diazo-3-Ketoglutaric Acid Dimethyl Ester
CAS No.	83878-89-1
Molecular Formula	C7H8N2O5
Molecular Weight	200.15 g/mol
Synonyms	Dimethyl 2-diazo-3-oxopentanedioate; 2-Diazo-3-oxoglutaric Acid Dimethyl Ester; Dimethyl 2-Diazo-3-oxoglutarate; 2-Diazo-3-oxopentanedioic Acid Dimethyl Ester; DKGA Dimethyl Ester; 3-Oxoglutaric Acid 2-Diazo-, Dimethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Diazo-3-Ketoglutaric Acid Dimethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality systems are designed to meet the stringent requirements of research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light) and should be handled with appropriate precautions to minimize exposure to light and moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.