Description

2-[(4-Bromophenyl)Chloromethylene]Butyraldehyde is a specialized organic building block featuring both bromoaryl and chloromethylene functional groups. This compound matters as a versatile intermediate for synthesizing complex molecules, particularly in pharmaceutical and agrochemical research where its unique halogenated structure enables targeted chemical modifications. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the bromophenyl moiety contributes to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the preparation of functionalized polymers or organic electronic materials due to its reactive aldehyde and halogen groups.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-[(4-Bromophenyl)Chloromethylene]Butyraldehyde
CAS No.	83846-59-7
Molecular Formula	C11H10BrClO
Molecular Weight	273.55 g/mol
Synonyms	4-Bromo-α-(chloromethylene)benzenebutanal; 2-[(4-Bromophenyl)(chloro)methylene]butanal; Butyraldehyde, 2-[(4-bromophenyl)chloromethylene]-; (4-Bromobenzylidene)butyraldehyde chloride derivative; α-Chloro-4-bromocinnamaldehyde (related structure); 4-Bromo-α-chlorocinnamaldehyde (common name); 2-(4-Bromobenzylidene)-2-chlorobutanal
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Bromophenyl)Chloromethylene]Butyraldehyde undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.