Description

2-Amino-n-(2-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydrobenzothiophene core. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation therapeutic candidates, where its structural complexity enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric applications.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in organic chemistry.
• API Manufacturing: Employed in the scaled-up production of target active pharmaceutical ingredients under GMP conditions.
• Biochemical Research: Utilized as a tool compound for probing biological pathways and enzyme interactions in vitro.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Amino-n-(2-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide
CAS No.	83822-36-0
Molecular Formula	C₁₆H₁₈N₂O₂S
Molecular Weight	302.39 g/mol
Synonyms	2-Amino-N-(2-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 4,5,6,7-Tetrahydro-2-amino-N-(2-methoxyphenyl)-1-benzothiophene-3-carboxamide; 83822-36-0; 2-Amino-N-(2-methoxyphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; Tetrahydrobenzothiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(2-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and compliance documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.