Description

Salvinorin A is a highly potent, naturally occurring diterpenoid compound known for its unique pharmacological profile. Its significance lies in its role as a selective κ-opioid receptor (KOR) agonist, making it a critical reference standard and research chemical for neuropharmacological studies. This product is essential for pharmaceutical R&D laboratories, academic institutions, and analytical facilities focused on receptor pharmacology, neuroscience, and the development of novel therapeutic agents.

Application

• Pharmacological Research: Used as a selective κ-opioid receptor (KOR) agonist in receptor binding assays and functional studies to investigate pain pathways, mood disorders, and addiction.
• Neuroscience Studies: Serves as a key tool compound for exploring the physiological and behavioral effects of KOR activation in preclinical models.
• Analytical Reference Standard: Employed as a high-purity certified reference material (CRM) for method development, validation, and quality control in HPLC, LC-MS, and GC-MS analyses.
• Pharmaceutical Development: Acts as a lead compound or molecular template for the design and synthesis of novel analgesic or neuropsychiatric therapeutics.
• Forensic Analysis: Utilized as an analytical standard for the identification and quantification of Salvinorin A in forensic and toxicology laboratories.
• Biochemical Assays: Applied in high-throughput screening (HTS) campaigns to discover new modulators of the κ-opioid receptor pathway.

Basic Information

Product Name	Salvinorin A
CAS No.	83729-01-5
Molecular Formula	C23H28O8
Molecular Weight	432.47 g/mol
Synonyms	Divinorin A; Salvinorin; Salvia divinorum factor A; 2-Benzopyran-1-one, 4a,7a-epoxy-3,4,4b,5,6,7,7a,8,9,10-decahydro-6-hydroxy-4b,8,8-trimethyl-11-methylene-9-oxo-, (4aR,4bS,7S,7aS,9S,10aR)-(-)-; (4bS,7S,7aS,9S,10aR)-7-Hydroxy-4b,8,8-trimethyl-11-methylidene-3,4,4a,4b,5,6,7,7a,8,9,10,10a-dodecahydro-1H-9,4a-(epoxymethano)phenanthren-2-one
EINECS	Contact for details

Quality Control

Our Salvinorin A is produced and handled under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize the risk of oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.