Description

(R)-2-Methylaziridine is a chiral, non-racemic aziridine derivative, a versatile and high-value building block in organic synthesis. Its importance lies in its strained three-membered ring structure, which provides significant reactivity for ring-opening reactions and functional group transformations. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of chiral amines, amino alcohols, and complex bioactive molecules.

Application

• As a key chiral synthon in the asymmetric synthesis of pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• In the preparation of chiral ligands and catalysts for asymmetric catalysis.
• For the synthesis of novel agrochemicals, including herbicides and insecticides with specific stereochemistry.
• As a building block for advanced materials, such as chiral polymers and liquid crystals.
• In academic and industrial research for developing new methodologies in organic and medicinal chemistry.
• For the production of chiral chelating agents and complexing agents.

Basic Information

Product Name	(R)-2-Methylaziridine
CAS No.	83647-99-8
Molecular Formula	C3H7N
Molecular Weight	57.09 g/mol
Synonyms	(R)-(-)-2-Methylaziridine; (R)-Propyleneimine; (R)-1,2-Propylenimine; (R)-2-Methylazacyclopropane; (R)-2-Methylethylenimine; (R)-Aziridine, 2-methyl-; (2R)-2-Methylaziridine
EINECS	Contact for details

Quality Control

Our (R)-2-Methylaziridine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (e.e.), critical for chiral synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% e.e.
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.