Description

Ethanone, 2-Fluoro-1-(2-Hydroxyphenyl)- (9Ci) is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the ortho-hydroxy and fluoro substituents on the acetophenone scaffold, enabling precise molecular construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in fluorinated bioactive molecules.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in metal-catalyzed reactions and coordination chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry Studies: An important substrate for investigating new fluorination methodologies and the effects of fluorine substitution.
• Fine Chemical Synthesis: A versatile building block for creating complex, high-value aromatic compounds in custom synthesis projects.

Basic Information

Item	Detail
Product Name	Ethanone, 2-Fluoro-1-(2-Hydroxyphenyl)- (9Ci)
CAS No.	83505-27-5
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	2'-Hydroxy-2-fluoroacetophenone; 1-(2-Hydroxyphenyl)-2-fluoroethanone; 2-Fluoro-1-(2-hydroxyphenyl)ethanone; 2-Fluoro-2'-hydroxyacetophenone; o-Hydroxy-2-fluoroacetophenone; 2-Fluoro-1-(2-hydroxyphenyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Fluoro-1-(2-Hydroxyphenyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system supports cGMP standards for advanced intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be stored away from light. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.