Description

3-Chloro-1-(3-Fluorophenyl)-1-Oxopropane is a high-purity organic intermediate featuring both chloro and fluoro substituents on a propiophenone backbone. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals where the introduction of halogenated aromatic ketone motifs is critical.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a starting material for creating fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: Acts as an electrophilic component in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing specialty chemicals with specific halogenated architectures.

Basic Information

Product Name	3-Chloro-1-(3-Fluorophenyl)-1-Oxopropane
CAS No.	83406-26-2
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	3-Chloro-1-(3-fluorophenyl)propan-1-one; 3'-Fluoro-3-chloropropiophenone; 1-Propanone, 3-chloro-1-(3-fluorophenyl)-; 3-Chloro-3'-fluoropropiophenone; β-Chloro-3'-fluoropropiophenone; 3-Fluorophenyl 3-chloropropyl ketone; 3-Chloro-1-(3-fluorophenyl)propanone
EINECS	Contact for details

Quality Control

Our 3-Chloro-1-(3-Fluorophenyl)-1-Oxopropane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.