Description

1,8-Diazabicyclo[5.4.0]Undec-7-Ene (DBU) is a versatile, sterically hindered organic superbase widely recognized for its exceptional nucleophilicity and low nucleofugality. This compound matters for its crucial role as a non-nucleophilic base and catalyst in complex organic synthesis, enabling high-yield reactions under mild conditions. It is essential for R&D chemists and production engineers in the pharmaceutical, agrochemical, and polymer industries who require efficient deprotonation and elimination reactions.

Application

• Pharmaceutical Synthesis: As a catalyst and base in the production of active pharmaceutical ingredients (APIs), particularly for β-lactam antibiotics and other heterocyclic compounds.
• Polymer Chemistry: Catalyst for the production of polyurethanes, polycarbonates, and epoxy resins, where it promotes polymerization and cross-linking reactions.
• Agrochemical Manufacturing: Used in the synthesis of pesticides, herbicides, and fungicides as a key reagent for condensation and cyclization steps.
• Fine Chemical Production: Employed in the synthesis of flavors, fragrances, and dyes due to its ability to facilitate clean reactions with minimal by-products.
• Dehydrohalogenation Agent: Effective for the elimination of hydrogen halides to form alkenes and alkynes in complex molecular frameworks.
• Isocyanate Trimerization: Acts as a catalyst for converting isocyanates into isocyanurates, enhancing the thermal stability of resulting polymers.

Basic Information

Product Name	1,8-Diazabicyclo[5.4.0]Undec-7-Ene
CAS No.	83329-50-4
Molecular Formula	C9H16N2
Molecular Weight	152.24 g/mol
Synonyms	DBU; 1,8-Diazabicyclo[5.4.0]undec-7-ene; 2,3,4,6,7,8,9,10-Octahydropyrimido[1,2-a]azepine; Diazabicycloundecene; 1,8-Diazabicyclo[5.4.0]undec-7-en; NSC 102811; U-CAT SA1; Polycat SA1
EINECS	280-452-2

Quality Control

Our 1,8-Diazabicyclo[5.4.0]Undec-7-Ene is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and industrial applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.520 - 1.524
Density (20°C)	1.018 - 1.022 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.