Description

Holothurin A2 is a triterpenoid glycoside, a bioactive marine natural product primarily sourced from sea cucumbers. This compound is of significant interest for its potent cytotoxic and antitumor properties, making it a valuable reference standard and research chemical in drug discovery. It is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors focused on oncology, marine pharmacology, and novel therapeutic agent development.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the investigation of new anticancer and antitumor agents.
• Biomedical Studies: Used in in vitro and in vivo studies to elucidate mechanisms of action related to cytotoxicity, apoptosis induction, and cell cycle arrest.
• Marine Natural Product Chemistry: A key compound for chemical ecology studies, biosynthesis research, and as a marker for the identification and standardization of sea cucumber extracts.
• High-Purity Analytical Standards: Employed in analytical laboratories for method development, validation, and quality control of related marine-derived products using techniques like HPLC and LC-MS.
• Preclinical Evaluation: Utilized in screening assays and preclinical models to assess efficacy, pharmacokinetics, and safety profiles of potential marine-based therapeutics.

Basic Information

Product Name	Holothurin A2
CAS No.	83323-87-9
Molecular Formula	C54H86O26S2Na2
Molecular Weight	~1221.3 g/mol
Synonyms	Holothurin A; Holothurin A2, disodium salt; Stichoposide A; 3β-[(O-β-D-Glucopyranosyl-(1→3)-O-β-D-glucopyranosyl-(1→4)-O-β-D-quinovopyranosyl-(1→2)-O-β-D-xylopyranosyl)oxy]-23-oxo-7,8-didehydroholosta-9(11),25-dien-16-one, 22,25-epoxide, 3-sulfate disodium salt; Sea Cucumber Saponin A2; Thelenotoside A; EINECS Not Listed

Quality Control

Our Holothurin A2 is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, MS for identity confirmation, and NMR for structural verification. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.