Description

[Bromo(Difluoro)Methyl]Benzene is a versatile fluorinated aromatic building block, specifically a benzyl bromide derivative where the methylene hydrogens are replaced by fluorine atoms. This molecular architecture provides unique reactivity, making it a critical intermediate for introducing the difluoromethylbenzyl moiety into more complex molecules. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise fluorination to modulate the biological activity, metabolic stability, and physicochemical properties of their target compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with enhanced lipophilicity and metabolic resistance.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the difluoromethyl group can improve efficacy and environmental profile.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitutions to construct complex aromatic and heteroaromatic systems.
• Fluorine Chemistry Research: A valuable tool in academic and industrial R&D for studying the effects of fluorination on molecular properties.

Basic Information

Product Name	[Bromo(Difluoro)Methyl]Benzene
CAS No.	83170-17-6
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	α-Bromo-α,α-difluorotoluene; (Bromodifluoromethyl)benzene; Benzyl Bromide, α,α-difluoro-; Difluorobenzyl Bromide; 1-(Bromodifluoromethyl)benzene; Benzene, (bromodifluoromethyl)-; Toluene, α-bromo-α,α-difluoro-
EINECS	Contact for details

Quality Control

Our [Bromo(Difluoro)Methyl]Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.