Description

L-Tyrosine, n-(2-Diazo-3,3,3-Trifluoro-1-Oxopropyl)-o-(4-Hydroxy-3-Iod Ophenyl)-3,5-Diiodo- is a specialized, high-purity iodinated and diazotized tyrosine derivative designed for advanced research and synthesis. This compound is critical for applications requiring precise molecular tagging and as a key intermediate in the development of novel bioactive molecules and diagnostic agents. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on radiopharmaceuticals, targeted drug delivery systems, and biochemical probe development.

Application

• Radiopharmaceutical Precursor: Serves as a crucial intermediate in the synthesis of iodine-123 or iodine-131 labeled compounds for diagnostic imaging and therapeutic applications.
• Bioconjugation & Probe Synthesis: Used for labeling peptides, proteins, and antibodies due to its reactive diazo and iodine functional groups, enabling the creation of targeted molecular probes.
• Pharmaceutical Intermediate: Acts as a building block in the research and development of novel thyroid hormone analogs and other iodinated therapeutic agents.
• Biochemical Research: Employed in studies of enzyme mechanisms, receptor binding assays, and metabolic pathway tracing where a stable, iodinated tyrosine derivative is required.
• Material Science Research: Potential use in the development of advanced polymers and functional materials with specific photochemical or electronic properties.

Basic Information

Product Name	L-Tyrosine, n-(2-Diazo-3,3,3-Trifluoro-1-Oxopropyl)-o-(4-Hydroxy-3-Iod Ophenyl)-3,5-Diiodo-
CAS No.	83093-58-7
Molecular Formula	C12H6F3I3N3O4
Molecular Weight	720.90 g/mol
Synonyms	3,5-Diiodo-L-tyrosine, N-[2-diazo-3,3,3-trifluoro-1-oxopropyl] derivative; 3,5-Diiodo-O-(4-hydroxy-3-iodophenyl)-N-(2-diazo-3,3,3-trifluoropropionyl)-L-tyrosine; L-Tyrosine, N-(2-diazo-3,3,3-trifluoro-1-oxopropyl)-O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-; Diazotized Diiodotyrosine Trifluoroacetyl Derivative; 83093-58-7; (2S)-2-[[(2E)-2-Diazo-3,3,3-trifluoropropanoyl]amino]-3-[4-hydroxy-3-iodo-5-[(4-hydroxy-3-iodophenyl)ethynyl]phenyl]propanoic acid (isomeric form).
EINECS	Contact for details

Quality Control

Our L-Tyrosine derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation, residual solvent analysis, and specific tests for heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications and supporting regulatory documentation for preclinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.