Description

Methanesulfonamide, 1,1,1-Trifluoro-n-Phenoxy- is a specialized fluorinated sulfonamide derivative, a key building block in advanced organic synthesis. Its unique structure, combining a trifluoromethyl group with a phenoxy linkage, makes it a valuable precursor for creating molecules with enhanced stability and specific electronic properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a key precursor in the manufacture of advanced herbicides and fungicides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Material Science Research: Used in the development of specialty polymers and liquid crystals, where its structural motifs can influence material properties like thermal stability and dielectric constant.
• Organic Light-Emitting Diode (OLED) Materials: Investigated as a building block for electron-transport or host materials in OLED devices due to its potential electronic characteristics.
• Cross-Coupling Reactions: Functions as a substrate or reagent in palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to construct complex biaryl systems.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on understanding the influence of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	Methanesulfonamide, 1,1,1-Trifluoro-n-Phenoxy-
CAS No.	83076-97-5
Molecular Formula	C8H6F3NO3S
Molecular Weight	253.20 g/mol
Synonyms	N-(Phenoxy)-1,1,1-trifluoromethanesulfonamide; 1,1,1-Trifluoro-N-phenoxymethanesulfonamide; Phenoxy(trifluoromethyl)sulfonylamine; α,α,α-Trifluoro-N-phenoxymethanesulfonamide; Trifluoromethanesulfonamide, N-phenoxy-; N-Phenoxytrifluoromethanesulfonamide; 83076-97-5
EINECS	Contact for details

Quality Control

Every batch of Methanesulfonamide, 1,1,1-Trifluoro-n-Phenoxy- is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles as determined by techniques including HPLC, GC, and NMR, is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.