Description

5-(tert-Butyldimethylsilyloxy)-1-Pentanol is a valuable organosilicon-protected alcohol intermediate, specifically featuring a tert-butyldimethylsilyl (TBDMS) ether protecting group on a primary hydroxyl function. This compound is critical for synthetic chemists as it enables the selective protection and deprotection of alcohols during multi-step synthesis, particularly in the construction of complex molecules. It is primarily utilized in the research and development of pharmaceuticals, agrochemicals, and advanced organic materials where precise control over functional group reactivity is required.

Application

• Pharmaceutical Synthesis: Key intermediate in the multi-step synthesis of active pharmaceutical ingredients (APIs), protecting sensitive hydroxyl groups during reactions with other functional groups.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where its protecting group strategy aids in building specific molecular architectures.
• Organic Electronics & Material Science: Serves as a building block for synthesizing specialized monomers and polymers used in organic light-emitting diodes (OLEDs) and other functional materials.
• Peptide & Carbohydrate Chemistry: Employed in the synthesis of complex natural products, peptides, and oligosaccharides that require orthogonal protection strategies.
• Academic & Industrial R&D: A fundamental reagent in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Fine Chemical Production: Acts as a precursor for the manufacture of other high-value, specialty chemicals and advanced intermediates.

Basic Information

Product Name	5-(tert-Butyldimethylsilyloxy)-1-Pentanol
CAS No.	83067-20-3
Molecular Formula	C11H26O2Si
Molecular Weight	218.41 g/mol
Synonyms	5-[(1,1-Dimethylethyl)dimethylsilyl]oxy-1-pentanol; 1-Pentanol, 5-[(1,1-dimethylethyl)dimethylsilyl]oxy-; 5-(TBDMS-oxy)-1-pentanol; 5-(tert-Butyldimethylsiloxy)-1-pentanol; 5-Hydroxypentyl tert-butyldimethylsilyl ether; 5-(tert-Butyldimethylsilyloxy)pentan-1-ol; TBDMS-protected 5-hydroxypentanol
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butyldimethylsilyloxy)-1-Pentanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is characterized using advanced analytical techniques, including NMR, GC, and HPLC, to verify identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.