Description

Ethylboronic Acid Pinacol Ester is a versatile organoboron reagent, specifically a boronic ester, widely used in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the parent boronic acid, making it a crucial building block for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific carbon-boron bond transformations.
• Material Science Research: Employed in the creation of organic electronic materials, polymers, and liquid crystals where precise molecular assembly is critical.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable ethyl group transfer reagent for forming carbon-carbon bonds between aryl/vinyl halides and the ethyl moiety.
• Chemical Library Development: Utilized in medicinal chemistry for the parallel synthesis and diversification of compound libraries for drug discovery.
• Catalyst and Ligand Preparation: Acts as a precursor in the synthesis of specialized catalysts and ligands used in asymmetric synthesis.

Basic Information

Product Name	Ethylboronic Acid Pinacol Ester
CAS No.	82954-89-0
Molecular Formula	C8H17BO2
Molecular Weight	156.03 g/mol
Synonyms	Ethylboronic Acid Pinacol Ester; Ethylboronic Acid Pinanediol Ester (common misnomer); Ethyl-4,4,5,5-Tetramethyl-1,3,2-dioxaborolane; 2-Ethyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; EthylBpin; Ethyl BPin; Pinacol Ethylboronate; Ethylboronate Pinacol Ester
EINECS	Contact for details

Quality Control

Our Ethylboronic Acid Pinacol Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.