Description

Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-1-Cyclohexen-1-Yl)- (9Ci) is a specialized fluorinated enol ester building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a trifluoroacetyl group adjacent to a cyclic enol, makes it a valuable precursor for introducing the trifluoromethyl moiety into complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing bioactive molecules containing the CF3 group, which is known to enhance metabolic stability, lipophilicity, and binding affinity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on novel fluorination reactions and the study of fluorine's effects on molecular properties.
• Ligand and Catalyst Development: Utilized as a building block for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-1-Cyclohexen-1-Yl)- (9Ci)
CAS No.	82726-79-2
Molecular Formula	C8H9F3O2
Molecular Weight	194.15 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-hydroxycyclohex-1-en-1-yl)ethan-1-one; 1-(2-Hydroxy-1-cyclohexen-1-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(2-hydroxy-1-cyclohexenyl)ethanone; Trifluoroacetylcyclohexenol; TFAE Cyclohexenol Derivative; Fluorinated Cyclohexenone Acetate; 82726-79-2; 2-Hydroxycyclohex-1-en-1-yl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-(2-Hydroxy-1-Cyclohexen-1-Yl)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.