Description

1-(4-Fluorophenyl)-3-Phenyl-Prop-2-Yn-1-One is a high-purity fluorinated aromatic ketone building block, specifically a diarylpropynone derivative. This compound is valued for its unique molecular scaffold, which is integral to advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and inflammatory pathways.
• Agrochemical Research: Used in the synthesis of experimental herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed as a building block for creating molecular probes and inhibitors to study enzyme function and protein interactions in biological systems.
• Academic & Industrial R&D: A versatile starting material for methodological development in organic chemistry, including catalysis and new bond-forming reactions.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-Phenyl-Prop-2-Yn-1-One
CAS No.	82677-84-7
Molecular Formula	C15H9FO
Molecular Weight	224.23 g/mol
Synonyms	4-Fluorochalcone; (E)-1-(4-Fluorophenyl)-3-phenylprop-2-en-1-one; 4'-Fluorochalcone; 3-Phenyl-1-(4-fluorophenyl)-2-propen-1-one; p-Fluorochalcone; 1-(4-Fluorophenyl)-3-phenyl-2-propen-1-one; 4-Fluoro-3-phenylacrylophenone; NSC 408696
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-3-Phenyl-Prop-2-Yn-1-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor purity grades to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.