Description

Flurithromycin is a semi-synthetic macrolide antibiotic derived from erythromycin, distinguished by the presence of a fluorine atom which enhances its antimicrobial potency and pharmacokinetic profile. This compound is valued for its broad-spectrum activity against Gram-positive and some Gram-negative bacteria, including strains resistant to other antibiotics. It is primarily utilized in pharmaceutical research and development for creating advanced antibacterial formulations targeting respiratory and skin infections.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of oral and topical antibacterial medications.
• Key intermediate in the research and synthesis of novel macrolide antibiotic derivatives.
• Reference standard in analytical laboratories for quality control and method development (HPLC, LC-MS).
• Biochemical research tool for studying bacterial protein synthesis and macrolide resistance mechanisms.
• Development of veterinary pharmaceuticals for treating bacterial infections in livestock.

Basic Information

Product Name	Flurithromycin
CAS No.	82664-20-8
Molecular Formula	C37H67FNO13
Molecular Weight	752.93 g/mol
Synonyms	Flurithromycin; 8-Fluoroerythromycin; 2'-Ethyl 11,12-carbonate erythromycin 9-oxime; Flurithromycinum; Fluritromicina; Flurithromycin (USAN); Abbott 56268; 4''-O-Acetyl-9-deoxo-9a-aza-9a-homoerythromycin A 9-oxime 11,12-cyclic carbonate 2'-ethylsuccinate
EINECS	Contact for details

Quality Control

Our Flurithromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.