Description

2-(4-Methyl-3-Nitrophenyl)Acetonitrile is a versatile nitrile intermediate featuring both a reactive cyano group and a nitro-substituted aromatic ring, making it a valuable synthon for constructing complex molecular architectures. Its primary value lies in its role as a key building block for the synthesis of advanced pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific functional groups into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those requiring a nitrile or amine functional group after reduction.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the nitrophenyl moiety is integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and other colored compounds, leveraging the nitro group for chromophore development.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure and polarizable groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	2-(4-Methyl-3-Nitrophenyl)Acetonitrile
CAS No.	82613-51-2
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	(4-Methyl-3-nitrophenyl)acetonitrile; 2-(4-Methyl-3-nitrophenyl)ethanenitrile; 3-Nitro-4-methylphenylacetonitrile; 4-Methyl-3-nitrobenzyl cyanide; α-(4-Methyl-3-nitrophenyl)acetonitrile; 82613-51-2; (4-Methyl-3-nitrophenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 2-(4-Methyl-3-Nitrophenyl)Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support our clients' regulatory submissions with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.