Description

4-tert-Butyl-1H-Imidazol-2-Amine is a versatile and highly functionalized imidazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a key precursor for the development of pharmaceuticals, agrochemicals, and specialty materials, enabling the creation of complex molecules with targeted properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate the imidazole pharmacophore into new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole core is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new fungicides, herbicides, and plant growth regulators that leverage its heterocyclic structure.
• Ligand in Catalysis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands or other coordinating agents used in transition metal catalysis for coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, ionic liquids, or metal-organic frameworks (MOFs) due to its electron-donating and coordinating capabilities.
• Chemical Biology Probe Development: Useful for creating molecular probes and inhibitors to study biological pathways and enzyme functions.

Basic Information

Product Name	4-tert-Butyl-1H-Imidazol-2-Amine
CAS No.	82560-19-8
Molecular Formula	C7H13N3
Molecular Weight	139.20 g/mol
Synonyms	2-Amino-4-tert-butylimidazole; 4-tert-Butyl-2-imidazolamine; 4-(1,1-Dimethylethyl)-1H-imidazol-2-amine; 4-tert-Butyl-1H-imidazol-2-ylamine; 2-Amino-4-(tert-butyl)-1H-imidazole; 4-tert-Butylimidazol-2-amine; 4-tert-Butyl-2-aminoimidazole
EINECS	Contact for details

Quality Control

Our 4-tert-Butyl-1H-Imidazol-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.