Description

4-Nitrobenzyl 2-Diazoacetoacetate is a specialized diazo compound of significant interest in advanced organic synthesis. Its core value lies in its utility as a versatile photochemical precursor and a key building block for generating reactive carbene intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for applications in photolithography, photoaffinity labeling, and the synthesis of complex heterocyclic structures.

Application

• Photolithography and Microfabrication: Acts as a photoactive compound (PAC) in advanced photoresist formulations for semiconductor and microelectronics manufacturing.
• Photoaffinity Labeling (PAL): Serves as a critical reagent for studying biomolecular interactions, enzyme active sites, and drug-receptor binding mechanisms.
• Carbene Chemistry: A key precursor for generating reactive carbene species under thermal or photolytic conditions, used in cyclopropanation and C-H insertion reactions.
• Fine Chemical Synthesis: Employed as a building block in the multi-step synthesis of complex pharmaceutical intermediates and agrochemicals.
• Polymer Science: Used in the development of specialty polymers and functional materials via photopolymerization or cross-linking reactions.
• Research & Development: A valuable tool in academic and industrial R&D labs for developing new synthetic methodologies and catalytic processes.

Basic Information

Product Name	4-Nitrobenzyl 2-Diazoacetoacetate
CAS No.	82551-63-1
Molecular Formula	C11H9N3O5
Molecular Weight	263.21 g/mol
Synonyms	2-Diazo-3-oxobutanoic Acid 4-Nitrobenzyl Ester; 4-Nitrobenzyl Diazoacetoacetate; p-Nitrobenzyl 2-Diazoacetoacetate; 2-Diazoacetoacetic Acid 4-Nitrobenzyl Ester; Diazoacetoacetic Acid p-Nitrobenzyl Ester; (4-Nitrobenzyl) 2-diazo-3-oxobutanoate; DNQ Derivative (related class)
EINECS	Contact for details

Quality Control

Our 4-Nitrobenzyl 2-Diazoacetoacetate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for research and high-tech applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling should be performed under subdued lighting or amber glass containers. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.