Description

(2R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-2α-Hydroxy-4α-(Hydroxymethyl)-3α,4Aα,8,8-Tetramethylnaphthalen-1(2H)-One is a high-purity, stereochemically defined decalin derivative that serves as a critical chiral building block and synthetic intermediate. Its complex, polycyclic structure with multiple functional groups makes it invaluable for constructing sophisticated molecular architectures in advanced organic synthesis. This compound is primarily sought by research and development chemists in the pharmaceutical and fine chemical industries for applications in drug discovery, process chemistry, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex stereochemistry.
• Advanced Organic Synthesis: Used as a sophisticated building block for constructing complex polycyclic frameworks found in natural products and specialty chemicals.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and testing of new asymmetric catalytic reactions.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing high-value, structurally unique odorants and flavor compounds due to its decalin core.
• Material Science Research: Investigated as a monomer or precursor for creating novel polymers with specific stereoregularity and thermal properties.
• Chemical Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-2α-Hydroxy-4α-(Hydroxymethyl)-3α,4Aα,8,8-Tetramethylnaphthalen-1(2H)-One
CAS No.	82526-31-6
Molecular Formula	C15H26O3
Molecular Weight	254.37 g/mol
Synonyms	(2R,3aS,4S,4aR,8aS)-2-Hydroxy-4-(hydroxymethyl)-3a,4a,8,8-tetramethyldecahydronaphthalen-1(2H)-one; (2R,3aS,4S,4aR,8aS)-2-Hydroxy-4-(hydroxymethyl)-3a,4a,8,8-tetramethyloctahydro-1H-naphthalen-1-one; Decalin-1-one derivative; Polyhydroxylated decalin derivative; Chiral decalin intermediate; Stereoisomer of Ambrox precursor
EINECS	Contact for details

Quality Control

Every batch of (2R)-3,4,4A,5,6,7,8,8Aβ-Octahydro-2α-Hydroxy-4α-(Hydroxymethyl)-3α,4Aα,8,8-Tetramethylnaphthalen-1(2H)-One is manufactured under a strict quality management system and undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing results for chiral purity, chemical purity (HPLC), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.