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n-Decyl-β-D-Maltopyranoside CAS NO 82494-09-5
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CAS No.:82494-09-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Decyl-β-D-Maltopyranoside is a high-purity, non-ionic detergent widely used in biochemical and biophysical research for membrane protein solubilization and crystallization. This compound matters because it offers a critical balance of mildness and efficacy, effectively stabilizing sensitive proteins without denaturing them. It is essential for researchers and manufacturers in structural biology, pharmaceutical development, and diagnostic assay formulation who require reliable, high-quality surfactants for challenging membrane protein studies.
Application
- Membrane Protein Solubilization: A key reagent for extracting and stabilizing integral membrane proteins from lipid bilayers for downstream analysis.
- Protein Crystallography: Used to create micelles that facilitate the growth of high-quality crystals of membrane proteins for X-ray diffraction studies.
- Biophysical Characterization: Employed in techniques like surface plasmon resonance (SPR) and analytical ultracentrifugation to maintain protein native state.
- Virus and Vaccine Research: Acts as a mild detergent in the disassembly and study of enveloped viruses and in vaccine adjuvant formulations.
- Diagnostic Assays: Utilized in immunoassay buffers to reduce non-specific binding and improve signal-to-noise ratios.
- Chromatography: Serves as an additive in purification processes, such as size-exclusion chromatography, to prevent protein aggregation.
- Cell Lysis: Provides a gentle alternative to ionic detergents for lysing cells while preserving protein complexes and enzyme activity.
- Liposome Preparation: Used in the formation and stabilization of model membrane systems for drug delivery and membrane interaction studies.
Basic Information
| Product Name | n-Decyl-β-D-Maltopyranoside |
| CAS No. | 82494-09-5 |
| Molecular Formula | C22H42O11 |
| Molecular Weight | 482.57 g/mol |
| Synonyms | Decyl β-D-maltopyranoside; n-Decyl-β-D-maltoside; Decyl maltoside; DDM; n-Decyl-β-maltoside; C10-Maltoside; Decyl-β-maltopyranoside; β-n-Decyl maltoside |
| EINECS | Contact for details |
Quality Control
Our n-Decyl-β-D-Maltopyranoside is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically exceeding 98% (by HPLC). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity (IR, NMR), assay, critical micelle concentration (CMC), and limits for impurities like moisture and inorganic residues. We adhere to relevant quality standards for research-grade biochemicals to support your critical applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storing under an inert atmosphere or with desiccant. Keep away from strong oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Critical Micelle Concentration (CMC) | ~1.8 mM (in water at 25°C) |
| Heavy Metals (as Pb) | ≤ 10 ppm |
| Residue on Ignition | ≤ 0.1% |
| Biological Activity | Pass (Hemolytic activity test) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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