Description

Undecyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside CAS NO 152914-68-6 is a specialized non-ionic surfactant and glycoside derivative, synthesized by linking an undecyl chain to a modified N-acetylglucosamine sugar headgroup. This molecular structure is critical for its role as a highly effective, mild detergent for the solubilization and stabilization of membrane proteins without denaturing their native conformation. It is an essential reagent for structural biology research, pharmaceutical development, and the formulation of advanced biochemical assays where maintaining protein integrity is paramount.

Application

• Membrane Protein Solubilization: Primary application for extracting and solubilizing integral membrane proteins from lipid bilayers for biochemical and biophysical studies.
• Structural Biology: Used in the purification and crystallization of membrane proteins for X-ray crystallography and cryo-electron microscopy (cryo-EM).
• Biopharmaceutical Development: Employed in the formulation and stabilization of therapeutic proteins, including monoclonal antibodies and complex biologics.
• Cell Lysis & Organelle Isolation: Effective in gentle cell lysis protocols and the isolation of functional membrane-bound organelles.
• Liposome & Micelle Preparation: Serves as a key component in creating model membrane systems like liposomes and detergent micelles for drug delivery research.
• Diagnostic Assays: Utilized in immunoassays and other diagnostic kits to maintain antigen and antibody activity.

Basic Information

Product Name	Undecyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside
CAS No.	152914-68-6
Molecular Formula	C21H41NO7
Molecular Weight	419.56 g/mol
Synonyms	Undecyl-β-D-glucopyranoside, N-acetyl derivative; n-Undecyl 2-acetamido-2-deoxy-β-D-glucopyranoside; UDG; Undecyl N-Acetyl-β-D-glucosaminide; 2-Acetamido-2-deoxy-β-D-glucopyranoside undecyl ether; β-Undecylglucoside, N-acetyl-; Heptyl β-D-glucopyranoside tetramer derivative (informal); Glycoside-based detergent, C11-NAG
EINECS	Contact for details

Quality Control

Our Undecyl2-Acetamido-2-Deoxy-B-D-Glucopyranoside is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reproducible results in your most sensitive applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.