Description

1-Chloro-3-Methoxy-5-Methylbenzene is a versatile halogenated aromatic ether building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of its chloro, methoxy, and methyl substituents, which allow for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex aryl-ether backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its substituted benzene core is integral.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials and liquid crystals due to its aromatic and ether functionalities.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized dyes and colorants.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	1-Chloro-3-Methoxy-5-Methylbenzene
CAS No.	82477-66-5
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	3-Chloro-5-methoxytoluene; 5-Chloro-3-methylanisole; 1-Chloro-3-methoxy-5-methyl-benzene; 3-Methyl-5-chloroanisole; m-Chloro-m-methoxytoluene; 3-Chloroanisole, 5-methyl-; Benzene, 1-chloro-3-methoxy-5-methyl-
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Methoxy-5-Methylbenzene is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.15 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.