Description

1,1,1,2-Tetrafluoroethane (Pharmaceutical Excipient) is a high-purity, non-flammable propellant and solvent meeting stringent pharmaceutical standards. Its core value lies in providing a safe, inert, and highly volatile medium for the precise formulation and delivery of active pharmaceutical ingredients. This product is essential for manufacturers in the pharmaceutical and medical device industries, particularly for the development and production of metered-dose inhalers (MDIs), topical sprays, and other pressurized dosage forms.

Application

• Primary propellant in metered-dose inhalers (MDIs) for asthma and COPD medications.
• Solvent and propellant for topical pharmaceutical sprays, including anesthetic and antiseptic formulations.
• Carrier gas in medical aerosol products and diagnostic sprays.
• Precision cleaning agent for medical device manufacturing and assembly.
• Blowing agent in the production of pharmaceutical-grade polymer foams.
• Refrigerant in specialized laboratory and medical cooling applications.

Basic Information

Product Name	1,1,1,2-Tetrafluoroethane (Pharmaceutical Excipient)
CAS No.	82426-88-8
Molecular Formula	C2H2F4
Molecular Weight	102.03 g/mol
Synonyms	R-134a (Pharmaceutical Grade); HFC-134a; Norflurane; 1,1,1,2-Tetrafluoroethane; Suva 134a; Genetron 134a; Freon 134a; Dymel 134a
EINECS	Contact for details

Quality Control

Our pharmaceutical-grade 1,1,1,2-Tetrafluoroethane is manufactured and tested to meet or exceed the stringent requirements of global pharmacopoeias, including USP-NF and EP monographs. Production occurs in a cGMP-compliant environment, with rigorous quality testing covering identity, assay, purity, and residual solvents. A comprehensive Certificate of Analysis (COA) is provided with each batch, ensuring full traceability and compliance for your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and ignition points. Due to its highly volatile and gaseous nature under ambient conditions, containers must be kept upright and handled in accordance with pressure vessel regulations. Recommended storage temperature is 15-25°C.

Specification

Item	Specification
Description	Colorless gas
Identification (IR)	Conforms
Assay (GC)	≥ 99.9%
Water Content (KF)	≤ 10 ppm
Non-volatile Residue	≤ 10 ppm
Acidity (as HCl)	≤ 1 ppm
Chloride (Cl)	≤ 1 ppm
Heavy Metals (as Pb)	≤ 1 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.